NanoFlex Gel
Massage Gel with nano phytotransfersome technique!
NANOFLEX Gel
offers a promising mechanism for Transepidermal Drug Delivery System (TDDS) of natural anti-inflammatory and pain relieving therapeutics like Boswellia serrata extract which is called the PHYTOTRANSFEROSOMES.
NANOFLEX Gel could potentially improve the treatment of various inflammatory conditions and pain management for more joint comfort and flexibility with no side effects like those caused by oral analgesics.
Nanoflex restores your flexibility through 3 modes of action.
Reliefs
Boswellic acid with TDDC
Anti-inflammatory and Analgesic effect.
Lubricates
transfersomes
Nanoflex’s skin penetration is superior offering optimal lubrication while relieving discomfort.
SOOTHES
Menthol And Eucalyptus Oil
Counter-irritant Feel Cool then Warm..
Edge Activator:
A biocompatible surfactant to increase bi-layer flexibility and permeability.
Phospholipids:
Lecithin phospholipids which self assemble into a lipid bilayer in an aqueous environment and close to form elastic vesicles for joint lubrication.
The gel base contains Eucalyptus + Menthol giving a counter-irritant effect with Cool then warm sensation.
Boswellia serrate extract has been encapsulated by the Transfersomes which enable it to deliver to the Joint giving an instant relive.
NANOFLEX GEL has a superior penetration ability over than others to give instant relief
Why Nanoflex Gel should be your first choice to restore your flexibility?
1- A novel drug carrier or drug delivery technology (TDDS).
2- Highly deformable nature having the ability to carry and transport large molecules across skin.
3- The ability to penetrate deeply allows it to create a lubricating layer on cartilage surfaces, while also providing anti-inflammatory natural products.
4- Instant pain relief.
5- Offers an alternative to oral administration with potential for improved efficacy.
6- Has a Counterirritant effect.
7- Gives a long-lasting effect.
8- Fast absorption
Nanoflex is indicated for:
1- Chronic Body Pain caused by Rheumatic syndromes such as (Osteoarthritis, Rheumatoid arthritis)
2- BACK-ACHES
3- Neck Stiffness
4- MUSCLE CRAMPS FOR Those who practices sports.
5- For athletes: can use the Nanoflex Gel before and after training to help muscle relaxation and relief often tenderness.
Application
Spread a thin layer around the joint and do NOT rub it in. Allow to dry.
Drying Time
Once applied the correct amount should take roughly 10 minutes to air dry.
Frequency
You should look to apply NANOFLEX twice daily, in the morning and evening.
References
– AAPS PharmSciTech, Transfersomes: a Revolutionary Nanosystem for Efficient Transdermal Drug Delivery, Published: 01 December 2021, Volume 23, article number 7, (2022)
– Role of edge activators and surface charge in developing ultradeformable vesicles with enhanced skin delivery, G.M. El Zaafarany et al. / International Journal of Pharmaceutics 397 (2010) 164–172, © 2010 Elsevier B.V. All rights reserved.
– Formulation, characterization of glucosamine loaded transfersomes and in vivo evaluation using papain induced arthritis model, Sci Rep. 2022 Nov 17;12(1):19813. doi: 10.1038/s41598-022-23103-1. PMID: 36396950; PMCID: PMC9672044.
– Transfersomes: A Promising Nanoencapsulation Technique for Transdermal Drug Delivery, Submission received: 23 July 2020 / Revised: 3 September 2020 / Accepted: 5 September 2020 / Published: 9 September 2020
– Chitosan and Lecithin Ameliorate Osteoarthritis Symptoms Induced by Monoiodoacetate in a Rat Model. Molecules. 2020 Dec 4;25(23):5738. doi: 10.3390/molecules25235738. PMID: 33291821; PMCID: PMC7730914.
– Topical delivery of curcumin-loaded transfersomes gel ameliorated rheumatoid arthritis by inhibiting NF-κβ pathway. Nanomedicine (Lond). 2021 Apr;16(10):819-837. doi: 10.2217/nnm-2020-0316. Epub 2021 Apr 26. PMID: 33900118.
– Oral and topical boswellic acid attenuates mouse osteoarthritis, https://doi.org/10.1016/j.joca.2013.10.012, Osteoarthritis and Cartilage, Volume 22, Issue 1, January 2014, Pages 128-132